Single-cell datasets are growing in size, posing challenges as well as opportunities to biology researchers. ondisc (short for “on-disk single cell”) is an R package that empowers users to easily and efficiently compute on large-scale single-cell data. ondisc is especially well-suited to fixed memory and distributed CRISPR screen and differential expression analyses.

NOTE: This package currently is in beta version and undergoing testing by several research groups. We expect to release a stable version in 2023.


You can install the development version from Github with: